PALLADIUM-CATALYZED NUCLEOPHILIC-SUBSTITUTION OF NAPHTHYLMETHYL AND 1-NAPHTHYLETHYL ESTERS

Sodium dimethyl malonate reacted with naphthylmethyl and 1-naphthylethyl alcohol derivatives in DMF at 20-80-degrees-C, under palladium(0) / phosphine catalysis. to give the substitution products dimethyl naphthylmethyl- and 1-naphthylethylmalonates. respectively, in good (75-83%) yield.

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Bibliographic Details
Published inTetrahedron letters Vol. 33; no. 18; pp. 2509 - 2510
Main Authors LEGROS, JY, FIAUD, JC
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 28.04.1992
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
SODIUM DIMETHYL MALONATE
SUBSTITUTION
NAPHTHYLMETHYL AND 1-NAPHTHYLETHYL ESTERS
PALLADIUM PHOSPHINE CATALYST
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Summary:Sodium dimethyl malonate reacted with naphthylmethyl and 1-naphthylethyl alcohol derivatives in DMF at 20-80-degrees-C, under palladium(0) / phosphine catalysis. to give the substitution products dimethyl naphthylmethyl- and 1-naphthylethylmalonates. respectively, in good (75-83%) yield.
ISSN:0040-4039
DOI:10.1016/S0040-4039(00)92227-5