Investigations of the Chemistry of Alkyl Phosphites Toward Nitrogen-Containing Compounds: Efficient Approaches to [alpha]-Amino-, [beta]-Amino-, and/or Enaminophosphonates
In this study, we report recent investigations of the chemical reactivity of alkyl phosphites, mainly trialkyl and dialkyl phosphites, with molecules containing different nitrogen-containing compounds reported by us and other research groups over the past 25 years. Previous ground-breaking important...
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Published in | Synthetic communications Vol. 45; no. 17; p. 1929 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Philadelphia
Taylor & Francis Ltd
01.09.2015
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Subjects | |
Online Access | Get full text |
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Summary: | In this study, we report recent investigations of the chemical reactivity of alkyl phosphites, mainly trialkyl and dialkyl phosphites, with molecules containing different nitrogen-containing compounds reported by us and other research groups over the past 25 years. Previous ground-breaking important reports are also considered. The reviewed investigations in this article are grouped according to only the type of the nitrogen-functional groups [amines (primary, secondary, and tertiary amines), imines, amides, thioamides, nitriles, isocyanates, isothiocyanates, oximes, hydrazones, diazo, and azides] and not according to the site of attack or the final products. Furthermore, the present review article focuses on the synthesis of α-amino-, [beta]-amino-, and/or enaminophosphonates. These compounds have important roles in pharmaceutical chemistry. |
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ISSN: | 0039-7911 1532-2432 |
DOI: | 10.1080/00397911.2015.1027777 |