Fabrication of a Ti3C2Tx modified glassy carbon electrode for the sensitive electrochemical detection of quercetin

• Published in: New journal of chemistry Vol. 45; no. 43; pp. 20396 - 20401
• Main Authors: Sun, Yunxiu, Wang, Baoli, He, Xiaoli, Wang, Yitong, Chen, Lin, Zhu, Yuxin, Li, Guangjiu, Sun, Wei
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 09.11.2021
• Subjects: Coated electrodes; Electrochemical analysis; Electrochemistry; Electrodes; Electron transfer; Electrons; Glassy carbon; Mathematical analysis; Morphology
• ISSN: 1144-0546; 1369-9261
• DOI: 10.1039/d1nj04046d

In this study, two-dimensional MXene Ti3C2Tx was modified on a glassy carbon electrode (GCE) to improve its performance for electrochemical detection. The morphology and structure of Ti3C2Tx were characterized by SEM and TEM. A new modified electrode was then fabricated by coating MXene solution on GCE for quercetin detection. The performance of MXene/GCE was determined by various methods, which showed an enhanced electrochemical activity. Direct electrochemistry of quercetin was investigated, and a pair of well-shaped redox peaks appeared with a peak-to-peak separation of 67 mV. The detection of quercetin by this proposed electrode was studied in detail, and presented a lower detection limit of 33 nM (3S0/S) with electrochemical parameters such as the electron transfer number (n), electron transfer coefficient (α) and reaction rate constant (ks) calculated as 1.99, 0.65 and 0.29 s−1, respectively. MXene/GCE was successfully utilized for the analysis of quercetin content in Ginkgo tablet samples with recoveries from 100.92% to 104.66%. Besides, MXene/GCE showed good anti-interference performance, good stability and reproducibility for the detection of quercetin.