New methods of pathogenic bacteria elimination

The growing bacterial resistance to antibiotics calls for the elaboration of new pathogens elimination strategies. Some of these methods are based on the conjugative transfer of recombinant plasmids able to eliminate pathogenic recipients by plasmid run-away replication or by killing activity of pla...

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Bibliographic Details
Published inPolish journal of microbiology Vol. 53 Suppl; pp. 39 - 43
Main Authors Wolska, Krystyna I, Kraczkiewicz-Dowjat, Anna, Grudniak, Anna M, Sajkowska, Anna, Wiktorowicz, Tatiana
Format Journal Article
LanguageEnglish
Published Poland De Gruyter Poland 2004
Subjects
Bacteria - genetics
Bacteria - growth & development
Bacteria - metabolism
Bacterial Infections - therapy
Conjugation, Genetic - physiology
Gene Transfer, Horizontal - physiology
Plasmids - therapeutic use
Transformation, Bacterial - physiology
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Summary:The growing bacterial resistance to antibiotics calls for the elaboration of new pathogens elimination strategies. Some of these methods are based on the conjugative transfer of recombinant plasmids able to eliminate pathogenic recipients by plasmid run-away replication or by killing activity of plasmid-encoded bacteriocins. Using live bacteria as donors of plasmid vectors carrying killing determinants requires meeting many safety restrictions in order to eliminate potential biohazard.
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ISSN:1733-1331
2544-4646