Comparison of Machine Learning Models in Predicting Mental Health Sequelae Following Concussion in Youth

• Published in: AMIA Summits on Translational Science proceedings Vol. 2025; pp. 422 - 431
• Main Authors: Peng, Jin, Chen, Jiayuan, Yin, Changchang, Zhang, Ping, Yang, Jingzhen
• Format: Journal Article
• Language: English
• Published: United States American Medical Informatics Association 2025
• ISSN: 2153-4063; 2153-4063

Youth who experience concussions may be at greater risk for subsequent mental health challenges, making early detection crucial for timely intervention. This study utilized Bidirectional Long Short-Term Memory (BiLSTM) networks to predict mental health outcomes following concussion in youth and compared its performance to traditional models. We also examined whether incorporating social determinants of health (SDoH) improved predictive power, given the disproportionate impact of concussions and mental health issues on disadvantaged populations. We evaluated the models using accuracy, area under the curve (4UC) of the receiver operating characteristic (ROC), and other performance metrics. Our BiLSTM model with SDoH data achieved the highest accuracy (0.883) and 4UC-ROC score (0.892). Unlike traditional models, our approach provided real-time predictions at each visit within 12 months of the index concussion, aiding clinicians in making timely, visit-specific referrals for further treatment and interventions.