Therapeutic Effects of Vitamins and Nutritional Supplements on Sinusitis: A Narrative Review

Sinusitis, one of the most prevalent and undertreated disorders, is a term used to describe inflammation of the paranasal sinuses caused by either infectious or non-infectious sources. Bacterial, viral, or fungal infections can all cause sinusitis. Sinusitis is classified into 3 types: acute, subacu...

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Published inNutrition and metabolic insights Vol. 17; p. 11786388241263680
Main Authors Poudineh, Mohadeseh, Nikzad, Farhad, Parvin, Sadaf, Ghaheri, Mohammad, Sabbaghi, Shahin, Kazemi, Erfan, Ghodrati, Mohammad Mahdi, Mohammadyari, Fatemeh, Saeedpour, Sara, Mohammadpour, Shekoufeh, Sadat Farizani Gohari, Narjes, Heydarasadi, Farbod, Abolhasani, Dorsa, Olangian-Tehrani, Sepehr, Alinezhad, Armin
Format Journal Article
LanguageEnglish
Published United States SAGE Publications 2024
Subjects
Review
sinupret
nutritional supplements
vitamins
zinc supplements
Sinusitis
upper respiratory tract
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Summary:Sinusitis, one of the most prevalent and undertreated disorders, is a term used to describe inflammation of the paranasal sinuses caused by either infectious or non-infectious sources. Bacterial, viral, or fungal infections can all cause sinusitis. Sinusitis is classified into 3 types: acute, subacute, and chronic. Acute sinusitis lasts for less than 1 month, subacute sinusitis lasts from 1 to 3 months, and chronic sinusitis persists for over 3 months. This condition affects a significant portion of the population, imposing a substantial burden on the healthcare system. Antibiotics are the gold standard of bacterial sinusitis treatment. However, due to the rise of antimicrobial resistance, especially in immune-compromised patients, it is necessary to investigate potential adjunctive therapies. Based on the literature, vitamins (eg, vitamin D) have antioxidant, anti-inflammatory, and immune-modulatory properties and may effectively treat sinusitis and reduce mucous membrane inflammation. Besides vitamins, many other supplements like quercetin, sinupret, and echinacea have immunomodulatory effects and have shown promising results in sinusitis treatment. In this review, we look at the therapeutic role, safety, and efficacy of vitamins and nutritional supplements in sinusitis treatment.
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ISSN:1178-6388
1178-6388
DOI:10.1177/11786388241263680