TOWARD AN OBJECTIVE METHOD TO CLASSIFY TREMOR DOMINANT AND POSTURAL INSTABILITY AND GAIT DIFFICULTY SUBTYPES OF PARKINSON'S DISEASE: A PILOT STUDY

Discriminating the two subtypes of tremor dominant (TD) and postural instability/gait difficulty (PIGD) in Parkinson's disease (PD) at early stage is highly valuable and crucial for progression treatment of disease for caregivers. However, there is no objective method or a subtype-specific biom...

Full description

Saved in:
Bibliographic Details
Published inBiomedical sciences instrumentation Vol. 53; p. 138
Main Authors Rezvanian, Saba, Lockhart, Thurmon, Frames, Christopher, Soangra, Rahul
Format Journal Article
LanguageEnglish
Published United States 01.03.2017
Subjects
Fourier Transform and Center of pressure
Tremor dominant
postural instability and gait difficulty
Parkinson’s disease
Online AccessGet more information

Cover

More Information
Summary:Discriminating the two subtypes of tremor dominant (TD) and postural instability/gait difficulty (PIGD) in Parkinson's disease (PD) at early stage is highly valuable and crucial for progression treatment of disease for caregivers. However, there is no objective method or a subtype-specific biomarker yet available for identifying these two subtypes. A computational approach in frequency domain could be a good candidate to introduce biomarker since PD tremor had frequency range of 3-7 Hz. By using frequency component of the whole body Center Of Pressure (COP) signal, we propose a ratio between high and low frequency range. To evaluate this ratio, COP data of ten PD patients were utilized. The results suggest that identifying PD subtypes is attainable by using the frequency information of COP signals.
ISSN:0067-8856