New treatment for gastroesophageal reflux disease: Traditional Chinese medicine Xiaochaihu decoction

Gastroesophageal reflux disease (GERD) has a high prevalence worldwide. Li performed a well-designed study on the efficacy of modified Xiaochaihu decoction (MXD) for GERD, which showed that MXD is an optional therapy for GERD beyond proton pump inhibitors (PPIs). The herbal granule administration mo...

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Published inWorld journal of gastroenterology : WJG Vol. 28; no. 11; pp. 1184 - 1186
Main Authors Xu, Li-Ying, Yu, Bin-Yan, Cen, Lu-Sha
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Inc 21.03.2022
Subjects
Drugs, Chinese Herbal - therapeutic use
Gastroesophageal Reflux - diagnosis
Gastroesophageal Reflux - drug therapy
Humans
Letter to the Editor
Medicine, Chinese Traditional
Proton Pump Inhibitors - therapeutic use
New treatment
Traditional Chinese medicine
Xiaochaihu decoction
Modified Xiaochaihu decoction
Chronic disease
Gastroesophageal reflux disease
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Summary:Gastroesophageal reflux disease (GERD) has a high prevalence worldwide. Li performed a well-designed study on the efficacy of modified Xiaochaihu decoction (MXD) for GERD, which showed that MXD is an optional therapy for GERD beyond proton pump inhibitors (PPIs). The herbal granule administration mode minimized the bias from traditional herbal formula in clinical trials. One limitation of that study was that it lacked records of side effects and rescue medication. As a chronic disease with recurrent symptoms, GERD rehabilitation requires prolonged observation of the clinical course with MXD therapy.
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Corresponding author: Lu-Sha Cen, PhD, Attending Doctor, Department of Ophthalmology, The First Affiliated Hospital of Zhejiang Chinese Medical University, No. 54 Youdian Road, Hangzhou 310006, Zhejiang Province, China. cenlusa2@sina.com
Author contributions: Xu LY and Cen LS designed the research; Yu BY analyzed the data; Xu LY and Cen LS performed the research and wrote the letter; Cen LS revised the letter.
Supported by Scientific Research Project of Zhejiang TCM Science and Technology Programme, No. 2020ZB067, No. 2020ZT001, and No. 2021ZQ031; and National Natural Science Foundation of China, No. 81503522 and No. 82104862.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v28.i11.1184