Comparison of maternal and neonatal outcomes in women with HELLP syndrome and women with severe preeclampsia without HELLP syndrome

• Published in: Journal of prenatal medicine Vol. 4; no. 3; pp. 51 - 58
• Main Authors: Turgut, Abdulkadir, Demirci, Oya, Demirci, Elif, Uludoğan, Mehmet
• Format: Journal Article
• Language: English
• Published: Italy CIC Edizioni Internazionali 01.07.2010
• Subjects: Original; pre-eclampsia; neonatal outcome; maternal mortality; HELLP syndrome
• ISSN: 1971-3282; 1971-3290

To examine and to compare postpartum maternal and neonatal complications and morbidities in women with HELLP syndrome (HELLP group) and women with severe preeclampsia without HELLP syndrome (severe preeclamptic group). In this retrospective study, 111 patients in the HELLP group were matched with 467 patients in the severe preeclamptic group according to maternal and neonatal complications and morbidities. The rate of transfusion of blood products and acute renal failure was significantly greater in women with HELLP syndrome. One maternal mortality (0.9 % ) was found in women withHELLP syndrome, and no maternal mortality in women in severe preeclamptic group a. There were significant differences between the HELLP group and the severe preeclamptic group in neonatal mortality and morbidity. It was found that HELLP syndrome cases had significantly lower gestational age and fetal bodyweight. The simultaneous presence of HELLP syndrome and preeclampsia, along with oliguria, ascites, thrombocytopenia, elevated liver enzymes and caesarean delivery, was associated with post-partum complications. This study shows that maternal and neonatal morbidity and mortality are increased in pregnancies complicated by severe preeclampsia with HELLP syndrome. Neonatal mortality and morbidity appear to be influenced primarily by gestational age at delivery.