Pathology of angiosarcoma of the liver among vinyl chloride-polyvinyl chloride workers

We described the histologic features of 13 hepatic angiosarcomas which developed in workers engaged in the polymerization of vinyl chloride to polyvinyl chloride. Although the histologic features varied considerably in different portions of the angiosarcoma in the same liver and in the angiosarcomas...

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Bibliographic Details
Published inAnnals of the New York Academy of Sciences Vol. 246; p. 268
Main Authors Thomas, L B, Popper, H
Format Journal Article
LanguageEnglish
Published United States 31.01.1975
Subjects
Hemangiosarcoma - chemically induced
Hemangiosarcoma - pathology
Humans
Liver - pathology
Liver Neoplasms - chemically induced
Liver Neoplasms - pathology
Male
Middle Aged
Occupational Diseases - chemically induced
Polyvinyl Chloride - poisoning
Polyvinyls - poisoning
Vinyl Chloride - poisoning
Vinyl Compounds - poisoning
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Summary:We described the histologic features of 13 hepatic angiosarcomas which developed in workers engaged in the polymerization of vinyl chloride to polyvinyl chloride. Although the histologic features varied considerably in different portions of the angiosarcoma in the same liver and in the angiosarcomas of the liver from different patients, many features were similar such as sinusoidal, papillary, and cavernous growth patterns coincident with the precursor lesions of proliferation and atypia of sinusoidal lining cells.
ISSN:0077-8923
DOI:10.1111/j.1749-6632.1975.tb51102.x