Descriptive study of infection by SARS-CoV-2 in adults with diabetes

The main objective was to estimate the prevalence of diabetes mellitus (DM) among patients with COVID-19, to explore associated factors; and to describe clinical evolution of hospitalized patients. A cross-sectional study was conducted, which included adults confirmed with COVID-19 between 03/12/202...

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Published inMedicina Vol. 82; no. 1; p. 28
Main Authors Murujosa, Ana C, Pasik, Natalia I, Giuliani Quaglierini, Sofía A, Aime Risso, María, Burgos, Mariana A, Grande Ratti, María Florencia, Russo, María Paula
Format Journal Article
LanguageSpanish
Published Argentina 2022
Subjects
Adult
COVID-19
Cross-Sectional Studies
Diabetes Mellitus - epidemiology
Hospital Mortality
Hospitalization
Humans
Male
Middle Aged
Risk Factors
SARS-CoV-2
COVID-19
diabetes mellitus
hospital mortality
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Summary:The main objective was to estimate the prevalence of diabetes mellitus (DM) among patients with COVID-19, to explore associated factors; and to describe clinical evolution of hospitalized patients. A cross-sectional study was conducted, which included adults confirmed with COVID-19 between 03/12/2020 and 10/15/2020, at Hospital Italiano de Buenos Aires. From 6009 people with COVID-19, 408 had previous diagnosis of DM, yielding a prevalence of 6% (95%CI 6-7), higher prevalence was associated with age (12% in = 60 years and 3% in < 60 years; p = 0.01). In-hospital mortality was 6% (95%CI 6-7), being 15% in DM and 6% compared in non-diabetics (p < 0.01). Associated factors with DM were cardiovascular variables such as male sex, hypertension, smoking, chronic renal failure, heart failure, previous coronary disease; and clinical variables proxy of frailty such as: age, dementia and previous institutionalization (all with p < 0.01). Only 23% (96/408) of DM had an HbA1c measurement in the last 3 months and 76% in the last year, with an average 8.6%, and 25% in goal (HbA1c = 7%). Management was mostly in-hospital (59%), with an average hospital stay of 12 days, with the following complications during hospitalization: 6% presented a hypoglycemic value (< 70 mg/dl), 42% required oxygen therapy, 19 % went to intensive care unit, 15% required invasive mechanical ventilation (mean 11 days), and 25% (95%CI 20-31) of in-hospital mortality (mean 82 years).
ISSN:1669-9106