Detritic synovitis and rare skeletal diseases

Detritic synovitis represents a common finding in routine orthopedic pathology. Microscopically, the synovium displays cartilaginous and bony fragments in the synoviocyte layer or within the subsynovial soft tissues associated with resorptive changes. In the vast majority of cases, detritic synoviti...

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Bibliographic Details
Published inDer Pathologe Vol. 35 Suppl 2; p. 214
Main Author Zustin, J
Format Journal Article
LanguageGerman
Published Germany 01.11.2014
Subjects
Apatites - analysis
Arthropathy, Neurogenic - pathology
Bone Resorption - pathology
Cartilage, Articular - pathology
Crystallization
Diabetes Complications - pathology
Diagnosis, Differential
Fractures, Ununited - pathology
Humans
Ochronosis - pathology
Osteoarthritis - pathology
Osteonecrosis - pathology
Risk Factors
Synovial Membrane - pathology
Synovitis - pathology
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Summary:Detritic synovitis represents a common finding in routine orthopedic pathology. Microscopically, the synovium displays cartilaginous and bony fragments in the synoviocyte layer or within the subsynovial soft tissues associated with resorptive changes. In the vast majority of cases, detritic synovitis is associated with conditions leading to the destruction of articular cartilage and subchondral bone, such as severe osteoarthritis, collapsed avascular necrosis, diabetes mellitus, Charcot arthropathy or non-union fractures. The objective of this article is to review the literature regarding the microscopic findings in ochronosis, rapidly destructive hip disease and apatite crystal depositions that can enable a confident diagnosis or a limited differential diagnosis of detritic synovitis.
ISSN:1432-1963
DOI:10.1007/s00292-014-1977-0