Onychomatricoma, a rare lesion of the nail

Onychomatricoma is a rare fibroepithelial lesion of the nail matrix with peculiar clinical and histological features. Clinically, it is characterized by a longitudinal band of yellow thickening of the nail plate with transverse overcurvature and splinter hemorrhages. Nail avulsion exposes a villous...

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Bibliographic Details
Published inAnnales de pathologie Vol. 24; no. 4; p. 368
Main Authors Pommepuy, Isabelle, Roblet, Denis, Blaise, Sophie, Delage-Corre, Manuela, Bonnetblanc, Jean-Marie, Fayol, Jacqueline, Labrousse, François
Format Journal Article
LanguageFrench
Published France 01.09.2004
Subjects
Humans
Male
Middle Aged
Nail Diseases - pathology
Skin Neoplasms - pathology
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Summary:Onychomatricoma is a rare fibroepithelial lesion of the nail matrix with peculiar clinical and histological features. Clinically, it is characterized by a longitudinal band of yellow thickening of the nail plate with transverse overcurvature and splinter hemorrhages. Nail avulsion exposes a villous tumor of the matrix with filamentous digitations extending into multiple holes of the nail plate. Histologically, a thick keratogenous zone forms a thickened nail plate. The lesion in its proximal portion is characterized by deep epithelial invaginations and by a stroma organized in two layers. The distal zone corresponds to multiple fibroepithelial projections extending into the nail plate. The diagnosis can be difficult in the presence of misleading clinical features or when the specimen is incomplete or examined with an improper orientation. Surgical resection is the recommended treatment.
ISSN:0242-6498
DOI:10.1016/S0242-6498(04)93986-7