External validity of a prognostic score for acute heart failure based on the Epidemiology of Acute Heart Failure in Emergency Departments registry: the EAHFE-3D scale

To validate the EAHFE-3D scale, based on the Acute Heart Failure in Emergency Departments registry, in a cohort of patients attended for acute heart failure. Study of a multipurpose cohort of patients with acute heart failure in 3 hospitals in the Basque Country between 2011 and 2013. We extracted a...

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Published inEmergencias : revista de la Sociedad Espanola de Medicina de Emergencias Vol. 30; no. 2; p. 84
Main Authors García-Gutiérrez, Susana, Quintana López, José M, Antón-Ladislao, Ane, Gallardo Rebollal, María Soledad, Rilo Miranda, Irene, Morillas Bueno, Miren, Murga Eizagaetxebarria, Nekane, Palenzuela Arocena, Ricardo, Pulido, Esther, Barrio Beraza, Irantzu, Aguirre Larracoechea, Urko, Arostegui, Inmaculada
Format Journal Article
LanguageEnglish
Published Spain 01.04.2018
Subjects
Acute Disease
Blood Pressure
Emergency Service, Hospital
Female
Heart Failure - blood
Heart Failure - mortality
Humans
Male
Oxygen - blood
Prognosis
Registries
Respiration, Artificial - statistics & numerical data
Retrospective Studies
Sodium - blood
Spain - epidemiology
Spain
Validation
Estudio de validación
Decompensated heart failure
Clinical decision-making
Insuficiencia cardiaca descompensada
Toma de decisión clínica
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Summary:To validate the EAHFE-3D scale, based on the Acute Heart Failure in Emergency Departments registry, in a cohort of patients attended for acute heart failure. Study of a multipurpose cohort of patients with acute heart failure in 3 hospitals in the Basque Country between 2011 and 2013. We extracted age, baseline New York Heart Association functional class, systolic blood pressure, baseline arterial oxygen saturation, sodium level in blood, and emergency department treatments (noninvasive mechanical ventilation, use of inotropic agents and vasopressors) in order to calculate each patient's EAHFE-3D score. The main outcome variable was mortality within 3 days of arrival at the emergency department. The patient sample for score validation consisted of 717 patients with complete information. The model's intercept was 0.5 (95% CI, -2.7 to 3.7) and the slope was 1.3 (95% CI, 0.4 to 2.2). The area under the receiver operating characteristic curve was 0.76 (95% CI, 0.58 to 0.94). The EAHFE-3D scale's ability to discriminate was good in this patient sample and similar to that reported by the authors who developed the scale; however, calibration was poor. The scale should be studied further before it is applied in clinical practice.
ISSN:2386-5857