Juvenile distal cerebral ischemia: angiographic features. A study of 55 cases

This study of juvenile distal cerebral ischaemia is based on 55 patients aged from 18 to 30 years. The authors describe the circumstances of discovery, as well as the clinical features and the course of the disease which may be severe and lead to non-resolutive neurological accidents and sometimes d...

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Bibliographic Details
Published inJournal of neuroradiology Vol. 19; no. 2; p. 118
Main Authors Arnott, G, Gozet, G, Lombart, B, Lambert, I, Blondel, M, Delandsheer, E, Leys, D
Format Journal Article
LanguageEnglish
Published France 01.03.1992
Subjects
Adolescent
Adult
Angiography, Digital Subtraction
Arteries - pathology
Brain Ischemia - diagnosis
Brain Ischemia - diagnostic imaging
Brain Ischemia - pathology
Cerebral Angiography
Diagnosis, Differential
Female
Humans
Male
Skin - blood supply
Tomography, X-Ray Computed
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Summary:This study of juvenile distal cerebral ischaemia is based on 55 patients aged from 18 to 30 years. The authors describe the circumstances of discovery, as well as the clinical features and the course of the disease which may be severe and lead to non-resolutive neurological accidents and sometimes dementia. Paraclinical evaluation includes capillaroscopy, finger and toe pads biopsy (which clearly shows a pathological process with fibrocellular promontories narrowing the lumen of arterioles), and above all angiography which displays two typical signs: arterial narrowness and bands of peripheral ischaemia. In advanced forms of the disease angiography reveals classical signs of ischaemic lesions, but charateritically these are very distal. Associated abnormalities of the carotid siphon can also be found. Finally, positive CT scans show an isolated widening of the sulci which is fairly suggestive of the disease.
ISSN:0150-9861