DroPhEA: Drosophila phenotype enrichment analysis for insect functional genomics

• Published in: Bioinformatics Vol. 27; no. 22; pp. 3218 - 3219
• Main Authors: Weng, Meng-Pin, Liao, Ben-Yang
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 15.11.2011
• Subjects: Animals; Anopheles - genetics; Anopheles - physiology; Bioinformatics; Biological and medical sciences; Contact; Displays; Drosophila; Drosophila melanogaster; Drosophila melanogaster - genetics; Enrichment; Evolution, Molecular; Feeding Behavior; Fundamental and applied biological sciences. Psychology; General aspects; Genes; Genes, Insect; Genome, Insect; Genomics - methods; Insects; Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects); Mutation; On-line systems; Phenotype; Software; Enrichment; Phenotype; Arthropoda; Insecta; Functional analysis; Invertebrata; Drosophila melanogaster; Diptera; Drosophilidae
• ISSN: 1367-4803; 1460-2059; 1367-4811
• DOI: 10.1093/bioinformatics/btr530

DroPhEA is a core module of a web application that facilitates research in insect functional genomics through enrichment analysis on mutant phenotypes of fruit fly (Drosophila melanogaster). The phenotypes investigated in the analyses can be predefined by FlyBase or customized by users. DroPhEA allows users to specify mutation or ortholog types, displays enriched term results in a hierarchical structure and supports analyses on gene sets of all insect species with a fully sequenced genome. Availability: http://evol.nhri.org.tw/phenome/DroPhEA/ Contact: liaoby@nhri.org.tw Supplementary Information: Supplementary data are available at Bioinformatics online.