The I-131 rose bengal excretion test is not dead

One hundred and thirty I-131 Rose Bengal Excretion Studies (RBI) were performed on 84 patients over nine years. In 90% (56/60) of cases with biliary atresia, the 72-hour RBI was less than or equal to 7%. In only 12.5% (3/24) of cases with neonatal hepatitis was the 72-hour RBI less than or equal to...

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Published inClinical nuclear medicine Vol. 10; no. 3; p. 171
Main Authors Antico, V F, Denhartog, P, Ash, J M, Gilday, D L, Houle, S
Format Journal Article
LanguageEnglish
Published United States 01.03.1985
Subjects
Bile Ducts - abnormalities
Female
Hepatitis - congenital
Hepatitis - diagnosis
Humans
Infant
Infant, Newborn
Iodine Radioisotopes
Male
Rose Bengal
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Summary:One hundred and thirty I-131 Rose Bengal Excretion Studies (RBI) were performed on 84 patients over nine years. In 90% (56/60) of cases with biliary atresia, the 72-hour RBI was less than or equal to 7%. In only 12.5% (3/24) of cases with neonatal hepatitis was the 72-hour RBI less than or equal to 7%. The accuracy of the test was 91% with a specificity of 88%. Thirty patients later were studied following a Kasai procedure. The RBI test reliably predicted the patency of the anastomosis. The authors conclude that the 72-hour RBI is a reliable test in the diagnosis of biliary atresia and in the documentation of biliary patency following surgery, provided adequate care is taken in stool collection and measurement.
ISSN:0363-9762
DOI:10.1097/00003072-198503000-00007