In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: 5-ALA; 68Ga-labelled carbon nanoparticles; 99mTc-FAP inhibitor; 99mTc-labeled iFAP; [3H]ifenprodil; [61Cu]Cu-DOTA-NOC; [61Cu]Cu-DOTA-TATE; [61Cu]Cu-DOTA-TOC; [68Ga]Ga-MAA; ABC-transporter; Alzheimer’s disease; amyloid-beta; animal model; astrocyte; biodistribution; Biology, life sciences; blood–brain barrier; copper-61; diabetes; drug development; drug-induced liver injury; extracellular vesicles (EVs); FAP; FDG; fluorescein; fluorescence guided surgery; fluorine-18; glioblastoma; GluN1/2B receptors; hepatotoxicity; heterobivalent peptide; high resolution; hybrid imaging; I-124; imaging; intra-arterial (I.A.) administration; intravenous (I.V.) administration; lipophilicity; liquid targets; liver function; magnetic resonance imaging; Mathematics and Science; metabolism; microglia; microvasculature imaging; multimodal imaging; n/a; nanoparticle; neurodegenerative diseases; neuroinflammation; neurotransmitter receptors; NIR-AZA; NMDA; organic anion-transporting polypeptide; oxime; PET; PET imaging; PET/CT; pharmacokinetics; photoacoustic; positron emission tomography; positron emission tomography (PET); post-processing; PSMA; psychiatric disorders; radiometals; receptor occupancy; Reference, Information and Interdisciplinary subjects; Research and information: general; SLC-transporter; SPECT; synaptic density; tumor microenvironment; umbilical cord mesenchymal stem cell (UCMSC); V/Q PET/CT; vascular imaging; σ1 and σ2 receptors
• ISBN: 9783036573908; 3036573909; 3036573917; 9783036573915
• DOI: 10.3390/books978-3-0365-7390-8

This Special Issue published one editorial, eight articles and four reviews from approximately one hundred authors. It aimed to provide cutting-edge research on pre-clinical development and the clinical translation of radiopharmaceuticals within the molecular imaging community. The Special Issue covered radioligand development, existing radiotracer optimization, imaging agent evaluation in animal models, the clinical production of radiopharmaceuticals, and investigative research on the use of molecular imaging probes in human subjects. We appreciate all the authors’ significant contributions to this Special Issue and hope the readers will enjoy the content.