Influence of Prenatal Noise and Music on the Expressions of c-Fos and Nitric Oxide Synthase in the Hippocampus of Rat Pups

The expressions of c-Fos and nitric oxide synthase (NOS) represent neuronal activity and play a crucial role in the shaping of the development of brain. During the late pregnancy, stresses may influence neuronal activity of prenatal rats. In the present study, the effects of prenatal noise and music...

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Published in동의생리병리학회지 Vol. 21; no. 5; pp. 1291 - 1296
Main Authors Su Mi Kim, Sam Jun Lee, Hong Kim, Seung Soo Baek, Yun Hee Sung, Jin Woo Lee, Young Sick Kim, Sung Eun Kim, Mal Soon Shin, Chang Ju Kim, Choong Yeol Lee
Format Journal Article
LanguageEnglish
Published 한의병리학회 01.10.2007
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ISSN1738-7698
2288-2529

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Abstract The expressions of c-Fos and nitric oxide synthase (NOS) represent neuronal activity and play a crucial role in the shaping of the development of brain. During the late pregnancy, stresses may influence neuronal activity of prenatal rats. In the present study, the effects of prenatal noise and music on the expressions of c-Fos and NOS in the hippocampus of rat pups were investigated. Exposure to the noise during pregnancy decreased c-Fos and NOS expressions in the hippocampus of rat pups, whereas exposure to music during pregnancy increased c-Fos and NOS expressions in the hippocampus of rat pups. The present results show that prenatal music stimulation may increase neuronal activity of rat offspring, whereas exposure to noise during pregnancy may reduce the neuronal activity of offspring. The present study suggests that prenatal stimuli including noise and music could affect the fetal brain development. KCI Citation Count: 0
AbstractList The expressions of c-Fos and nitric oxide synthase (NOS) represent neuronal activity and play a crucial role in the shaping of the development of brain. During the late pregnancy, stresses may influence neuronal activity of prenatal rats. In the present study, the effects of prenatal noise and music on the expressions of c-Fos and NOS in the hippocampus of rat pups were investigated. Exposure to the noise during pregnancy decreased c-Fos and NOS expressions in the hippocampus of rat pups, whereas exposure to music during pregnancy increased c-Fos and NOS expressions in the hippocampus of rat pups. The present results show that prenatal music stimulation may increase neuronal activity of rat offspring, whereas exposure to noise during pregnancy may reduce the neuronal activity of offspring. The present study suggests that prenatal stimuli including noise and music could affect the fetal brain development. KCI Citation Count: 0
Author Mal Soon Shin
Choong Yeol Lee
Yun Hee Sung
Su Mi Kim
Sung Eun Kim
Hong Kim
Young Sick Kim
Sam Jun Lee
Chang Ju Kim
Seung Soo Baek
Jin Woo Lee
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  fullname: Mal Soon Shin
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  fullname: Chang Ju Kim
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  fullname: Choong Yeol Lee
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Title Influence of Prenatal Noise and Music on the Expressions of c-Fos and Nitric Oxide Synthase in the Hippocampus of Rat Pups
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