加味復元通氣散의 항염작용에 대한 실험적 연구
The purpose of this research was to investigate the anti-inflammatory effects of Kamibokwontonggi-san(KBTS) which has been medicated the patient such as mastitis, mammary tuberculosis. KBTS in RAW264.7 cell inhibited IL-1β, IL-6, TNF-α, COX-2 and NOS-II mRNA genes expression in a concentration-depen...
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| Published in | 동의생리병리학회지 Vol. 21; no. 4; pp. 860 - 868 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | Korean |
| Published |
한의병리학회
01.08.2007
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1738-7698 2288-2529 |
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| Abstract | The purpose of this research was to investigate the anti-inflammatory effects of Kamibokwontonggi-san(KBTS) which has been medicated the patient such as mastitis, mammary tuberculosis. KBTS in RAW264.7 cell inhibited IL-1β, IL-6, TNF-α, COX-2 and NOS-II mRNA genes expression in a concentration-dependent manner. KBTS inhibited NO production significantly at 100, 50 ㎍/㎖ and ROS production in a concentration-dependent manner. KBTS inhibited IL-1β, IL-6 and TNF-α production significantly in serum of acute anti-inflammation-induced mice and the survival rate at the 3rd day on LPS-induced lethal endotoxemia. These results suggest that Kamibokwonntonggi-san (KBTS) can be useful in treating a lot of women diseases caused by inflammation such as mastitis, mammary tuberculosis, pelvic inflammatory disease and pelvic tuberculosis. KCI Citation Count: 2 |
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| AbstractList | The purpose of this research was to investigate the anti-inflammatory effects of Kamibokwontonggi-san(KBTS) which has been medicated the patient such as mastitis, mammary tuberculosis. KBTS in RAW264.7 cell inhibited IL-1β, IL-6, TNF-α, COX-2 and NOS-II mRNA genes expression in a concentration-dependent manner. KBTS inhibited NO production significantly at 100, 50 ㎍/㎖ and ROS production in a concentration-dependent manner. KBTS inhibited IL-1β, IL-6 and TNF-α production significantly in serum of acute anti-inflammation-induced mice and the survival rate at the 3rd day on LPS-induced lethal endotoxemia. These results suggest that Kamibokwonntonggi-san (KBTS) can be useful in treating a lot of women diseases caused by inflammation such as mastitis, mammary tuberculosis, pelvic inflammatory disease and pelvic tuberculosis. KCI Citation Count: 2 |
| Author | 김수민(Soo Min Kim) 유동열(Dong Youl Yoo) 이정은(Jung Eun Lee) 신선미(Sun Mi Shin) 김지혜(Ji Hye Kim) 임현정(Hyun Jung Lim) |
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| Title | 加味復元通氣散의 항염작용에 대한 실험적 연구 |
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