타 장기 원발암을 동반한 위암환자의 임상적 특성

• Published in: Annals of surgical treatment and research Vol. 74; no. 2; pp. 105 - 109
• Main Authors: 임진호(Jin Ho Lim), 성관수(Kwan Su Sung), 김택현(Taeg Hyun Kim), 송교영(Kyo Young Song), 강한철(Han Chol Kang), 김승남(Seung Nam Kim), 박조현(Cho Hyun Park)
• Format: Journal Article
• Language: Korean
• Published: 대한외과학회 01.02.2008
• Subjects: 일반외과학; Second primary cancer; Gastric cancer; Risk factor
• ISSN: 2288-6575; 2288-6796

Purpose: The aim of this study was to clarify the risk factors and clinicopathologic features of gastric cancer patients with a second primary cancer (SPC). Methods: The data on 2455 patients with gastric cancer was analyzed retrospectively with respect to the clinicopathologic features of the pathologically proven SPC. Results: Of the 2,455 patients, there were 90 (3.7%) gastric cancer patients with SPC. Among them, 31 patients had synchronous cancers and 59 had metachronous cancers. Of the 59 metachronous cancers, 21 were found before the gastric surgery and 38 were found after the gastric surgery. The most prevalent SPC was colorectal cancer (28 cases) and followed by cancer in the liver (13 cases) kidney and pancreas (6 cases each, respectively). Among the 61 patients with SPC found after gastric cancer surgery, 31 cases (50%) were diagnosed within 2 years. On comparison of the clinicopathologic features, the patients with SPC tended to be older, more prone to have early gastric carcinoma and to have multiple gastric lesions. The survival rate of the patients with SPC and gastric cancer alone was not different; however, there was a significantly difference for the patients with early gastric cancer (61.7% vs. 91.3%, respectively, P＜ 0.05). Conclusion: For the patients who were older, had multiple primary lesions or they had early gastric cancer, evaluation for SPC, and especially in the colon and liver, should be considered during routine follow up. (J Korean Surg Soc 2008;74:105-109) KCI Citation Count: 0