편평세포암종을 닮은 섬유샘종의 광범위 편평상피화생

• Published in: Annals of surgical treatment and research Vol. 76; no. 1; pp. 56 - 60
• Main Authors: 차은정(Eun Jung Cha), 최금하(Keum Ha Choi), 윤현조(Hyun Jo Youn), 김동석(Dong Sug Kim), 문우성(Woo Sung Moon)
• Format: Journal Article
• Language: Korean
• Published: 대한외과학회 2009
• Subjects: 일반외과학; Breast; 유방; 섬유샘종; Fibroadenoma; Squamous metaplasia; 편평세포화생
• ISSN: 2288-6575; 2288-6796

We report a fibroadenoma with extensive squamous metaplasia in the breast. A 21-year-old woman presented with a mass of the left breast. Breast ultrasonography showed a 1.8×1.7 cm sized, well-circumscribed mass in left subareolar region. The mass was excised. Grossly, the mass was well circumscribed and the cut surfaces were grayish-white in color and elastic in consistency. Microscopically, the breast lesion showed the histological features of fibroadenoma. There were areas of extensive squamous metaplasia seen as isolated clusters or involving duct. But some metaplastic clusters surrounded by fibrous stroma were compressed and distorted and separation of cells into isolated clusters mimicked invasive carcinoma. Co-expression of CK 5/6, high molecular weight CK and p63 in areas of squamous metaplasia and normal myoepithelial cells supported myoepithelial cell origin of metaplastic cells. KCI Citation Count: 0