탄성 나노복합체를 이용한 인체 간 혈관 주형의 작성과 그 임상적 이용

• Published in: Annals of surgical treatment and research Vol. 69; no. 5; pp. 395 - 399
• Main Authors: 유희철(Hee Chul Yu), 나창운(Changwoon Nah), 조백환(Baik Hwan Cho)
• Format: Journal Article
• Language: Korean
• Published: 대한외과학회 01.11.2005
• Subjects: 일반외과학; 탄성체; 나노복합체; Nanocomposites; 간; Liver; Elastomer; 혈관주형; Vascular cast
• ISSN: 2288-6575; 2288-6796

Purpose: For a successful partial liver resection, familiarity with the many anatomical variations of the biliary and vascular components in the liver is important. The aim of this study was to fabricate a precisely reproduced model of a human hepatic vascular cast with a very fine structure using elastomeric nanocomposites. Methods: A model of the vascular structure of the human liver was prepared by injecting elastomeric nanocomposites latex into that of a human liver obtained from a cadaver dissection, followed by cross-linking of the elastomeric nanocomposites, and then leaching out the human tissues using a strong acid solution. Results: A produced new version of human vascular casts, with further improved performances in both the stability and mechanical property, was successfully produced by application of new elastomer nanocomposites techniques based on clay nano particles. The cast showed a much finer vascular structure and lasted longer. This new technique is expected to provide a useful protocol for the investigating of the real vascular structure of the human liver. Conclusion: A precisely reproduced vascular cast of the human liver will significantly help to solve surgical complications, such as hepatic congestion-induced vascular injury and bile leakage, and give a more precise simulation for anatomical hepatic resection. KCI Citation Count: 0