Primary cornea guttata in Japanese patients with cataract: specular microscopic observations

To evaluate the prevalence of primary cornea guttata (the first stage of Fuchs' dystrophy) in Japanese patients, we retrospectively examined specular photomicrographs of patients' cataracts. Primary cornea guttata in subjects without corneal inflammation was defined as dark areas, seen on...

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Bibliographic Details
Published inJapanese journal of ophthalmology Vol. 40; no. 4; p. 520
Main Authors Nagaki, Y, Hayasaka, S, Kitagawa, K, Yamamoto, S
Format Journal Article
LanguageEnglish
Published Japan 01.01.1996
Subjects
Adult
Aged
Aged, 80 and over
Cataract - complications
Cataract - pathology
Cell Count
Cornea - pathology
Endothelium, Corneal - pathology
Female
Fuchs' Endothelial Dystrophy - complications
Fuchs' Endothelial Dystrophy - epidemiology
Fuchs' Endothelial Dystrophy - pathology
Humans
Japan - epidemiology
Male
Middle Aged
Photomicrography
Prevalence
Retrospective Studies
Visual Acuity
Japan
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Summary:To evaluate the prevalence of primary cornea guttata (the first stage of Fuchs' dystrophy) in Japanese patients, we retrospectively examined specular photomicrographs of patients' cataracts. Primary cornea guttata in subjects without corneal inflammation was defined as dark areas, seen on specular microscopy, and irregular refractile dots, observed with slit-lamp microscopy. In 107 patients with cataract (211 eyes), primary cornea guttata was found in 4 women (7 eyes), aged 56 to 76 years. One eye of patient 4, who had a history of angle-closure glaucoma and laser iridotomy, had bullous keratopathy. We also examined 16 relatives (32 eyes) of these 4 affected patients (probands), and found 2 women (4 eyes) with primary cornea guttata. No hereditary influence was identified. We believe that the incidence of primary cornea guttata (Fuchs' dystrophy) in Japan is lower than that in North America.
ISSN:0021-5155