Genome evolution Global methylation in eutherian hybrids

O'Neill et al. propose that epigenetic pro-cesses help to drive karyotypic evolution in marsupials. Here we present evidence that global methylation patterns do not undergo dramatic changes in interspecific hybrids among three orders of placental mammals, indicating that the mechanisms underlyi...

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Bibliographic Details
Published inNature (London) Vol. 401; no. 6749; pp. 131 - 132
Main Authors Fundele, Reinald, Roemer, Irmgard, Grützner, Frank, Winking, Heinz, Haaf, Thomas, Orth, Annie, Skidmore, Lulu, Antczak, Doug
Format Journal Article
LanguageEnglish
Published England Nature Publishing Group 09.09.1999
Subjects
Animals
DNA Methylation
Evolution, Molecular
Genome
Hybridization, Genetic - genetics
Infertility, Male - genetics
Male
Mammals
Marsupialia
Retroelements - genetics
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Summary:O'Neill et al. propose that epigenetic pro-cesses help to drive karyotypic evolution in marsupials. Here we present evidence that global methylation patterns do not undergo dramatic changes in interspecific hybrids among three orders of placental mammals, indicating that the mechanisms underlying genome evolution may be different in placental mammals and marsupials.
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ISSN:0028-0836
1476-4687
DOI:10.1038/43607