Nitrilotriacetic acid functionalization on Fe3O4 nanoparticle via amino and carboxylic functionalization

Since chelating chemical had focused for enhancing bio-susceptibility and ability for the binding with biomaterials, in thisstudy, Nitrilotiriacetic acid (NTA) was utilized for the developing chelate ligand attached superparamagnetic nanoparticle. Inorder to conjugate NTA, carboxylic group was neede...

Full description

Saved in:
Bibliographic Details
Published inJournal of Ceramic Processing Research, 21(5) pp. 515 - 523
Main Authors Jin Soon Han, MiRae Youm, Hyun-Hee Choi, Yeon-Gil Jung, Sung-Churl Choi, Gye Seok An
Format Journal Article
LanguageEnglish
Published 세라믹연구소 01.10.2020
Subjects
재료공학
Online AccessGet full text

Cover

More Information
Summary:Since chelating chemical had focused for enhancing bio-susceptibility and ability for the binding with biomaterials, in thisstudy, Nitrilotiriacetic acid (NTA) was utilized for the developing chelate ligand attached superparamagnetic nanoparticle. Inorder to conjugate NTA, carboxylic group was needed on the surface of substrate particle for building peptide bond withamine group which was branched from the NTA structure. Therefore Fe3O4 nanoparticle was functionalized with various ofamine precursor (Polyethyleneimine (PEI), (3-Aminopropyl)triethoxysilane (APTES)), and carboxyl precursor (Polyacrylicacid (PAA)) before the conjugation of NTA. Then NTA conjugation behavior was estimated which is varied with the type ofamine precursor which affects to the surface properties. KCI Citation Count: 0
ISSN:1229-9162
2672-152X
DOI:10.36410/jcpr.2020.21.5.515