The acidity constant of fluorene-9-carboxylic acid in aqueous solution. Determination of the pKa of a sparingly soluble substance

The acid ionization constant of the carboxylic acid group of fluorene-9-carboxylic acid in aqueous solution at 25 °C was determined to be pK a  = 3.61, using a method based upon the increase in solubility of this sparingly soluble substance brought about by its ionization. This corrects an earlier c...

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Bibliographic Details
Published inCanadian journal of chemistry Vol. 71; no. 2; pp. 227 - 229
Main Authors Kresge, A. J, Pojarlieff, I. G, Rubinstein, E. M
Format Journal Article
LanguageEnglish
Published Ottawa, Canada NRC Research Press 01.02.1993
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Summary:The acid ionization constant of the carboxylic acid group of fluorene-9-carboxylic acid in aqueous solution at 25 °C was determined to be pK a  = 3.61, using a method based upon the increase in solubility of this sparingly soluble substance brought about by its ionization. This corrects an earlier considerably different value of this quantity determined by equating pK a with the pH measured at half-neutralization. The hazard inherent in the latter method when applied to sparingly soluble substances is discussed.
ISSN:0008-4042
1480-3291
DOI:10.1139/v93-033