Time course of end-tidal desflurane concentration during delivery and elimination according to the type and location of filters in a semiclosed circuit system

• Published in: Korean journal of anesthesiology pp. 392 - 396
• Main Authors: 박성욱, 정준영, 문은진, 강영진, 강종만
• Format: Journal Article
• Language: English
• Published: 대한마취통증의학회 01.08.2015
• Subjects: 마취과학
• ISSN: 2005-6419; 2005-7563
• DOI: 10.4097/kjae.2015.68.4.392

Background: The aim of this study was to determine whether the end-tidal concentration of desflurane would be affected by a breathing circuit system filter attached at two different positions in anesthetic breathing circuit systems. Methods: An artificial lung was ventilated under five different conditions. The first group was without any filter or desflurane (n = 5, sham), the second was with desflurane but without any filter (n = 10, control), the third group had a bacterial filter on the expiratory limb (n = 10), and the fourth and fifth groups had a viral/bacterial filter added on the expiratory limb (n = 10) or at the Y-piece of the breathing circuit (n = 10), respectively. In all groups except the sham, administration of 10% desflurane was performed for 5 minutes and then stopped for 5 minutes. Results: The mean (SD) end-tidal concentration of desflurane for the groups described above peaked at 0 (0), 9.8 (0.1), 9.8 (0.1), 8.5 (0.1), and 6.7% (0.1) (P < 0.001), respectively. There was no difference in the desflurane concentrations and the expired tidal volume over time between the control and bacterial group, but there was a significant difference between the control and the fourth and fifth groups (P < 0.001). Conclusions: Filters can affect the expiratory desflurane concentration during anesthesia. KCI Citation Count: 0