Examination of migraine before and after percutaneous foramen ovale closure in patients with cryptogenic stroke and patent foramen ovale

• Published in: Neurosonology Vol. 36; no. 2; pp. 44 - 47
• Main Authors: IGASAKI, Shota, YAGIHASHI, Takahito, SAITO, Takuya, KAWABATA, Yuichi, YAZAWA, Yukako
• Format: Journal Article
• Language: Japanese
• Published: Kurashiki The Japan Academy of Neurosonology 31.08.2023; Japan Science and Technology Agency
• Subjects: Ischemia; Migraine; Stroke
• ISSN: 0917-074X; 1884-3336
• DOI: 10.2301/neurosonology.36.44

Objectives: Patent foramen ovale (PFO), migraine, and ischemic stroke are interrelated. Although PFO closure has proven to be effective for secondary prevention of ischemic stroke in patients with cryptogenic stroke, the efficacy of PFO closure For migraine has not been established. This study aimed to evaluate the prevalence and changes in migraine before and after PFO closure in patients who underwent this procedure as a secondary prevention measure for cryptogenic stroke. Methods: Between November 2018 and March 2020, 11 consecutive patients with cryptogenic stroke who underwent transcatheter percutaneous PFO closure were enrolled and followed-up for more than six months. The diagnosis was made by a stroke neurologist, and PFO closure was performed according to relavent guidelines. Results: Four of the 11 patients had migraine, and all showed improvement after PFO closure using the Amplatzer PFO occluder. Conclusion: Some patients, especially those with cryptogenic stroke with PFO, may benefit from PFO closure for migraine.