Improvement of measurement method for hydroxylated polychlorinated biphenyls (OH-PCBs) in blood samples using LC/MS/MS

• Published in: Fukuoka igaku zasshi = Hukuoka acta medica Vol. 104; no. 4; p. 128
• Main Authors: Tobiishi, Kazuhiro, Suzuki, Shigeru, Todaka, Takashi, Hirakawa, Hironori, Hori, Tsuguhide, Kajiwara, Jumboku, Hirata, Teruaki, Iida, Takao, Uchi, Hiroshi, Furue, Masutaka
• Format: Journal Article
• Language: English
• Published: Japan 25.04.2013
• Subjects: Chemistry Techniques, Analytical - methods; Chromatography, Liquid; Humans; Hydroxylation; Polychlorinated Biphenyls - blood; Tandem Mass Spectrometry

Hydroxylated polychlorinated biphenyls (OH-PCBs) are well known as metabolites of PCBs in the human body. We improved a measurement method for OH-PCBs in blood samples using LC/MS/MS. A new 2 microm particle column was used, and the analytical conditions for the LC/MS/MS measurements were optimized....