Serum Concentrations of Ionized Calcium and Calcitonin under Basal and Hypercalcemic States in Oophorectomized Rats

It is very important to measure serum ionized calcium(iCa)accurately in the evaluation of calcitonin(CT)secretion in patients with abnormal Ca metabolism. To evaluate CT secretion in relation to iCa concentration, a newly developed calcium ion analyzer which simultaneously measured the pH level was...

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Bibliographic Details
Published inKAWASAKI MEDICAL JOURNAL Vol. 13; no. 3; pp. 103 - 109
Main Authors Masao FUKUNAGA, Nobuaki OTSUKA, Takako FURUKAWA, Rikushi MORITA
Format Journal Article
LanguageEnglish
Japanese
Published Kawasaki Medical Society 1987
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Summary:It is very important to measure serum ionized calcium(iCa)accurately in the evaluation of calcitonin(CT)secretion in patients with abnormal Ca metabolism. To evaluate CT secretion in relation to iCa concentration, a newly developed calcium ion analyzer which simultaneously measured the pH level was used. In oophorectomized rats(deficiency of E2), regardless of normal iCa level, a low basal CT concentration was found. However, normal capacity of CT secretion in response to hypercalcemic stimulation was observed. Therefore, this low basal CT level might be dependent not on the iCa level but on other factor.
ISSN:0385-0234