Prevention, Diagnosis, and Management of Radiation-Associated Cardiac Disease: JACC Scientific Expert Panel

Radiation-associated cardiac disease, a heterogeneous and complex disease, manifests years or even decades following radiation exposure to the chest. It is associated with a significantly higher morbidity and mortality. Often, the presentation is vague and overlaps with many diseases, presenting uni...

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Bibliographic Details
Published inJournal of the American College of Cardiology Vol. 74; no. 7; pp. 905 - 927
Main Authors Desai, Milind Y, Windecker, Stephan, Lancellotti, Patrizio, Bax, Jeroen J, Griffin, Brian P, Cahlon, Oren, Johnston, Douglas R
Format Journal Article Conference Proceeding Web Resource
LanguageEnglish
Published United States Elsevier Limited 20.08.2019
Elsevier USA
Subjects
Algorithms
Breast cancer
Calcification
Cancer therapies
Cardiology
Cardiomyopathy
Cardiovascular & respiratory systems
Cardiovascular disease
Cardiovascular Surgical Procedures
Chemotherapy
Coronary artery disease
Coronary vessels
Diagnostic systems
Disease control
Heart - diagnostic imaging
Heart diseases
Heart Diseases - diagnosis
Heart Diseases - etiology
Heart Diseases - therapy
Heart failure
Human health sciences
Humans
Lung Diseases - diagnostic imaging
Lung Diseases - etiology
Lymphatic system
Lymphoma
Medical diagnosis
Morbidity
Neoplasms - radiotherapy
Organs at Risk
Percutaneous treatment
Prevalence
Radiation
Radiation effects
Radiation Injuries - complications
Radiation Injuries - diagnosis
Radiation Injuries - therapy
Radiation therapy
Radiotherapy Dosage
Review
Risk Assessment
Risk Factors
Sciences de la santé humaine
Surgery
Systèmes cardiovasculaire & respiratoire
cardiac disease
diagnosis
management
radiation
review
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Summary:Radiation-associated cardiac disease, a heterogeneous and complex disease, manifests years or even decades following radiation exposure to the chest. It is associated with a significantly higher morbidity and mortality. Often, the presentation is vague and overlaps with many diseases, presenting unique diagnostic and management issues. As a result, a high index of suspicion followed by multimodality imaging is crucial, along with comprehensive screening to enable early detection. Timing of intervention should be carefully considered in these patients, because surgery is often complex with an emerging role of percutaneous interventions.
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scopus-id:2-s2.0-85071559521
ISSN:0735-1097
1558-3597
1558-3597
DOI:10.1016/j.jacc.2019.07.006