들쭉 추출물의 노인성 황반변성증 예방 효과

Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness among the elderly. In this study, extract of Vaccinium uliginosum L. that has potent antioxidant activity was evaluated as effective preventive supplement for AMD using AMD animal model induced by high fat diet...

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Bibliographic Details
Published inYaghag-hoi-ji Vol. 56; no. 5; pp. 314 - 319
Main Authors 김선미(Sun Mi Kim), 김혜주(Hye Ju Kim), 손미원(Miwon Son), 정세영(Se Young Choung)
Format Journal Article
LanguageKorean
Published The Pharmaceutical Society Of Korea 31.10.2012
대한약학회
Subjects
약학
Age-related macular degeneration
lipofuscin
Vaccinium uliginosum L
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Summary:Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness among the elderly. In this study, extract of Vaccinium uliginosum L. that has potent antioxidant activity was evaluated as effective preventive supplement for AMD using AMD animal model induced by high fat diet and UV A irradiation. Treatment with VU extract protected photoreceptor cells of retina and blocked the accumulation of lipofuscin pigment-granules induced by high fat diet and UV A light irradiation. This study suggests that VU extract may be a useful agent for prevention of progress of AMD.
Bibliography:KISTI1.1003/JNL.JAKO201217642691875
G704-000392.2012.56.5.001
ISSN:0377-9556
2383-9457