오배자의 항균활성 및 세포독성에 미치는 영향

• Published in: 동의생리병리학회지 Vol. 23; no. 2; pp. 412 - 415
• Main Authors: 김성진(Seong Jin Kim), 양하영(Ha Young Yang), 이선구(Seon Goo Lee)
• Format: Journal Article
• Language: Korean
• Published: 한의병리학회 2009
• Subjects: 한의학; antimicrobial; skin flora; chinensis galla; pitted keratolysis; cytotoxicity
• ISSN: 1738-7698; 2288-2529; 2283-2529

Chinensis galla has been used as an multi-functional herb, such as anti-inflammatory, anti-virus, and antitumor agent. This study was performed to antimicrobial and cytotoxicity effect in vitro. The results were summarized as follows : Chinensis galla was antimicrobial effect on Staphylococcus aureus subsp. aureus, Bacillus cereus, Bacillus subtilis, Staphylococcus epidermidis. Chinensis galla was antimicrobial effect on Kocuria rhizophila, Corynebacterium ammoniagenes. The extracts of Chinensis galla exhibited cytotoxicity on human dermal fibroblast at $10\;{\mu}{\ell}$ but not at $5\;{\mu}{\ell}$, and the same results was known under a microscope. Accordingly the results show Chinensis galla could antimicrobial effect but exhibited cytotoxicity on human dermal fibroblast at high concentration and it needs more research.