감기에 대한 연교패독산의 유효성 평가를 위한 community-based 이중맹검 위약 대조군 연구

• Published in: 동의생리병리학회지 Vol. 22; no. 1; pp. 234 - 245
• Main Authors: 배한호(Han Ho Bae), 강위창(Wee Chang Kang), 박양춘(Yang Chun Park)
• Format: Journal Article
• Language: Korean
• Published: 한의병리학회 2008
• Subjects: 한의학; Common cold; Yeonkyopaedok-san(YPS)
• ISSN: 1738-7698; 2288-2529; 2283-2529

Yeonkyopaedok-san(YPS) extract is widely used to treat the common cold. The purpose of this study was to evaluate the efficacy of YPS on the common cold. Two hundred Patients with common colds of recent onset were randomized to the double blind, placebo-controlled study. They received 800 mg YPS extract or placebo in capsules, orally dissolved 3 times a day for 7 days. The total symptom score was assessed by the physician, using a 5-point scale on start and finish. Resolution of cold symptoms based on subjective daily symptoms. Total symptom score was significantly decreased in YPS groups in comparison to that in placebo group (p=0.027). Headache (p=0.012), loss of appetite (p=0.037), eyeball discomfort (p=0.002) were more affected. Time to resolution of cold symptoms did not show significant effect (p=0.592). Adverse effects were less in the YPS group than placebo group (2% vs 3%). In this community-based, randomized controlled trial, YPS were effective in treating cold symptoms in college students.