아세트아미노펜 중독 청소년에서의 프로칼시토닌 상승

• Published in: 대한임상독성학회지 Vol. 17; no. 1; pp. 38 - 41
• Main Authors: 김소은, So Eun Kim, 이재백, Jae Baek Lee, 진영호, Young Ho Jin, 윤재철, Jae Chol Yoon, 조시온, Si On Jo, 정태오, Tae Oh Jeong
• Format: Journal Article
• Language: Korean
• Published: 대한임상독성학회 30.06.2019
• Subjects: Acetaminophen intoxication; Adolescent; Liver injury; Procalcitonin; 응급의학; Acetaminophen intoxication; Procalcitonin; Adolescent; Liver injury
• ISSN: 1738-1320; 2508-6332
• DOI: 10.22537/jksct.2019.17.1.38

Procalcitonin (PCT) is commonly employed in medical practice as a diagnostic biomarker of bacterial infection and also as a monitoring biomarker for antimicrobial therapy. There have been a few published reports concerning elevated PCT levels in people with acute liver injury caused by an overdose of acetaminophen. We report here on a case of PCT elevation in an adolescent with acute acetaminophen poisoning without any bacterial infection or liver injury. A 15-year-old girl had deliberately ingested 20 tablets of 650 mg acetaminophen (13 g) and she presented to our emergency department. The PCT level on admission was elevated to 65.64 ng/mL (reference range: 0-0.5 ng/mL). Her PCT level on the second day peaked up to 100 ng/mL and then it gradually decreased. There was no evidence of liver injury or infection on the computed tomography examination and other lab tests. The patient regained her good health and was discharged on the sixth day of hospitalization.