만성기침 환자에서 Chlamydia pneumoniae 감염률

• Published in: Tuberculosis and respiratory diseases Vol. 69; no. 6; pp. 426 - 433
• Main Authors: 이재영, Jae Young Lee, 김동규, Dong Gyu Kim, 박성훈, Sung Hoon Park, 황용일, Yong Il Hwang, 최정희, Jeong Hee Choi, 모은경, Eun Kyung Mo, 박용범, Yong Bum Park, 김철홍, Cheol Hong Kim, 정기석, Ki Suck Jung, 현인규, In Gyu Hyun, 신태림, Tae Rim Shin, 이명구, Myung Goo Lee, 장승훈, Seung Hun Jang, 박상면, Sang Myeon Park, 이창률, Chang Youl Lee, 박권오, Kwon Oh Park, 천승연, Seung Yeon Chun
• Format: Journal Article
• Language: Korean
• Published: 대한결핵 및 호흡기학회 30.12.2010; 대한결핵및호흡기학회
• Subjects: Chlamydia Infections; Cough; Polymerase Chain Reaction; 내과학; Chlamydia Infections; Cough; Polymerase Chain Reaction
• ISSN: 1738-3536; 2005-6184

Background: Persistent cough has recently been found to be associated with Chlamydia pneumoniae infection. We aimed to investigate the infection rate of C. pneumonia in adult patients with chronic cough. Methods: We recruited 68 patients with persistent cough lasting in excess of 3 weeks, who visited Kangdong Sacred Heart Hospital from January 2005 to August 2005. On the first visit, chest and paranasal sinuses radiography, skin prick test of common allergens, and induced sputum samples for C. pneumoniae were performed in all of patients. Further evaluation for diagnosis included a methacholine provocation test and eosinophil counts in induced sputum. Results: The most common cause of chronic cough was upper airway cough syndrome (UACS) (26.5%), followed by eosinophilic bronchitis (20.6%) and cough variant asthma (16.2%). Idiopathic chronic cough was the cause in 33.8% of patients. The mean duration of cough was 11.7 months. C. pneumoniae was isolated by polymerase chain reaction (PCR) from one patient who had upper respiratory air way syndrome. Conclusion: Chlamydia pneumoniae appears to have a minor role as a cause of chronic cough in patients.