A novel tricyclic derivative for PET imaging of the translocator protein

The translocator protein (TSPO) has attracted scientist's attention for Positron Emission Tomography (PET) imaging due to correlation with brain cancer, stroke, and neurodegeneration. Recently, GE-180, a novel tricyclic derivative has been developed as a new high affinity agent for the TSPO and...

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Bibliographic Details
Published inJournal of radiopharmaceuticals and molecular probes : JRMP Vol. 2; no. 1; pp. 37 - 42
Main Authors Kwon, Young-Do, Kim, Hee-Kwon
Format Journal Article
LanguageKorean
Published 대한방사성의약품학회 01.06.2016
Subjects
방사선과학
PET radiotracer
Positron emission tomography (PET)
GE-180
Translocator protein
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ISSN2384-1583
2508-3848

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Summary:The translocator protein (TSPO) has attracted scientist's attention for Positron Emission Tomography (PET) imaging due to correlation with brain cancer, stroke, and neurodegeneration. Recently, GE-180, a novel tricyclic derivative has been developed as a new high affinity agent for the TSPO and evaluated to confirm a possibility for the TSPO ligand. In this highlight review, several studies for the novel TSPO radiotracer are described.
Bibliography:KISTI1.1003/JNL.JAKO201634347491484
ISSN:2384-1583
2508-3848