폐 농양 치료 중 발생한 이차적 기질화 폐렴 1예

• Published in: Tuberculosis and respiratory diseases Vol. 62; no. 6; pp. 540 - 544
• Main Authors: 윤현영, 오숙의, 박종규, 신태림, 박상면, Yoon, Hyeon Young, Oh, Suk Ui, Park, Jong Gyu, Sin, Tae Rim, Park, Sang Myeon
• Format: Journal Article
• Language: Korean
• Published: 대한결핵및호흡기학회 01.06.2007
• Subjects: 내과학; Lung abscess; Organizing pneumonia; TBLB
• ISSN: 1738-3536; 2005-6184

The patient is a 62-year-old man with known diabetes mellitus who presented with a two-weeks-history of dyspnea, cough, and fever. He was diagnosed with a lung abscess in the right upper lobe and was treated with intravenous antibiotics. The patient's clinical and radiological findings improved within seven days after medical treatment. However, newly developed ground-glass opacity and infiltrations were observed in the right lower lung. Fourteen days after admission, the patient's symptoms and imaging finding became aggravated despite trestment with susceptible antibiotics for lung abscess. Trans-bronchial lung biopsy (TBLB) was performed in the lateral basal segment of the right lower lobe of the lung. A histologic photomicrograph showed organizing pneumonia, also called bronchiolitis obliterans with organizing pneumonia(BOOP), that became more definite as the terminal bronchioles and alveoli became occluded with masses of inflammatory cells and fibrotic tissue. The clinical symptoms and radiograph findings resolved quickly with prednisone treatment. We report a case of secondary organizing pneumonia diagnosed after TBLB following lung abscess treatment and provide a review of the literature. 폐농양의 치료 중에 발생하는 기질화 폐렴은 흔하게 관찰 되는 소견은 아니다. 기질화 폐렴은 특별한 원인 없이 발생하기도 하지만, 감염의 치료 과정에서 이차적 기질화 폐렴이 발생 할 수도 있다. 본 증례는 62세 남자 환자에서 폐농양을 치료하는 과정에서 발생한 기질화 폐렴을 경기관지 폐생검을 통해 확인하고 부신피질 호르몬을 투여로 효과적으로 치료한 예를 경험하였기에 보고하는 바이다.