신경독성물질에 의한 신경계장애 조기발견을 위한 색각검사의 활용가능성

• Published in: Journal of preventive medicine and public health Vol. 41; no. 6; pp. 397 - 406
• Main Authors: 이은희, 최경호, 채홍재, 백도명, Lee, Eun-Hee, Choi, Kyung-Ho, Chae, Hong-Jae, Paek, Do-Myung
• Format: Journal Article
• Language: Korean
• Published: 대한예방의학회 01.11.2008
• Subjects: 예방의학; Color vision impairment; Neurotoxic effects; Neurotoxic substances
• ISSN: 1975-8375; 2233-4521

This paper reviews the published literature that is concerned with color vision impairment from industrial and environmental exposure to neurotoxic substances, and we evaluated whether testing for color vision impairment could be an affordable procedure for assessing these neurotoxic effects. In general, most cases of congenital color vision impairment are red-green, and blue-yellow impairment is extremely rare. However, most of the acquired color vision impairment that is related to age, alcohol or environmental factors is blue-yellow impairment. Therefore, many studies have been performed to identify this relationship between exposure to neurotoxic substances, such as organic solvents and heavy metals, and the prevalence of blue-yellow color vision impairment. The test for color vision impairment is known to be very sensitive to the early signs of nervous system dysfunction and this can be useful for making the early diagnosis of neurotoxic effects from exposure to very low concentrations of toxic substances.