Regioselective Enzymatic Acylation of Multi-hydroxyl Compounds in Organic Synthesis

With current developments in enzyme-catalyzed reactions and techniques available for rational redesign of natural biocatalysts, the enzymatic biosynthesis can become one of the most valuable Synthetic methods. Enzymatic regioselective catalysis in organic media has played a key role in pursuing asym...

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Published inBiotechnology and bioprocess engineering Vol. 8; no. 1; pp. 1 - 8
Main Authors Park, Hyun-Gyu, Do, Jin-Hwan, Chang, Ho-Nam
Format Journal Article
LanguageKorean
Published 한국생물공학회 01.02.2003
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ISSN1226-8372
1976-3816

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Abstract With current developments in enzyme-catalyzed reactions and techniques available for rational redesign of natural biocatalysts, the enzymatic biosynthesis can become one of the most valuable Synthetic methods. Enzymatic regioselective catalysis in organic media has played a key role in pursuing asymmetric synthesis for active chiral compounds. Here, we shortly do-scribe some historical issues of the rapidly growing area, enzymatic catalysis in synthetic organic chemistry and then review researches that have been carried out in the regioselective enzymatic catalysis for the past two decades. An application of this technology to the modification of some potential target drug co m pound will be adios presented.
AbstractList With current developments in enzyme-catalyzed reactions and techniques available for rational redesign of natural biocatalysts, the enzymatic biosynthesis can become one of the most valuable Synthetic methods. Enzymatic regioselective catalysis in organic media has played a key role in pursuing asymmetric synthesis for active chiral compounds. Here, we shortly do-scribe some historical issues of the rapidly growing area, enzymatic catalysis in synthetic organic chemistry and then review researches that have been carried out in the regioselective enzymatic catalysis for the past two decades. An application of this technology to the modification of some potential target drug co m pound will be adios presented.
With current developments in enzyme-catalyzed reactions and techniques available forrational redesign of natural biocatalysts, the enzymatic biosynthesis can become one of the most valuable synthetic methods. Enzymatic regioselective catalysis in organic media has played a key role in pursuing asymmetric synthesis for active chiral compounds. Here, we shortly describe some historical issues of the rapidly growing area, enzymatic catalysis in synthetic organic chemistry and then review researches that have been carried out in the regioselective enzymatic catalysis for the past two decades. An application of this technology to the modification of some potential target drug compound will be also presented. KCI Citation Count: 44
Author Do, Jin-Hwan
Chang, Ho-Nam
Park, Hyun-Gyu
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Keywords regioselective synthesis
drug modification
enzymatic synthesis
Sugar acylation
glycoside
jineol
Language Korean
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Snippet With current developments in enzyme-catalyzed reactions and techniques available for rational redesign of natural biocatalysts, the enzymatic biosynthesis can...
With current developments in enzyme-catalyzed reactions and techniques available forrational redesign of natural biocatalysts, the enzymatic biosynthesis can...
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Title Regioselective Enzymatic Acylation of Multi-hydroxyl Compounds in Organic Synthesis
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