Regioselective Enzymatic Acylation of Multi-hydroxyl Compounds in Organic Synthesis

With current developments in enzyme-catalyzed reactions and techniques available for rational redesign of natural biocatalysts, the enzymatic biosynthesis can become one of the most valuable Synthetic methods. Enzymatic regioselective catalysis in organic media has played a key role in pursuing asym...

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Bibliographic Details
Published inBiotechnology and bioprocess engineering Vol. 8; no. 1; pp. 1 - 8
Main Authors Park, Hyun-Gyu, Do, Jin-Hwan, Chang, Ho-Nam
Format Journal Article
LanguageKorean
Published 한국생물공학회 01.02.2003
Subjects
생물공학
regioselective synthesis
drug modification
enzymatic synthesis
Sugar acylation
glycoside
jineol
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ISSN1226-8372
1976-3816

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Summary:With current developments in enzyme-catalyzed reactions and techniques available for rational redesign of natural biocatalysts, the enzymatic biosynthesis can become one of the most valuable Synthetic methods. Enzymatic regioselective catalysis in organic media has played a key role in pursuing asymmetric synthesis for active chiral compounds. Here, we shortly do-scribe some historical issues of the rapidly growing area, enzymatic catalysis in synthetic organic chemistry and then review researches that have been carried out in the regioselective enzymatic catalysis for the past two decades. An application of this technology to the modification of some potential target drug co m pound will be adios presented.
Bibliography:KISTI1.1003/JNL.JAKO200311921571117
G704-000785.2003.8.1.007
ISSN:1226-8372
1976-3816