rBST 투여가 숫사슴의 혈액 내 IGF-I 함량에 미치는 영향

• Published in: Journal of animal science and technology Vol. 47; no. 3; pp. 439 - 446
• Main Authors: 신형태, 최송환, 정기환, 안재남, 백순용, Shin, H.T, Cui, S.H, Chung, K.W, Ahn, J.N, Baig, S.Y
• Format: Journal Article
• Language: Korean
• Published: 한국축산학회 01.06.2005
• Subjects: 축산학; Red deer; IGF-I; Sika deer; rBST; Antler
• ISSN: 1598-9429; 2672-0191; 2093-6281

This study was conducted to elucidate the influence of recombinant bovine somatotropin (rBST) on the plasma IGF-I profiles in deer stags. Slow release rBST (250mg each) preparations were injected subcutaneously during the antler's non-growing period and growing period. It was observed that significant increases in the plasma IGF-I concentrations were occurred right after injections of the rBST irrespective of antler's non-growing period or growing period. When the rBST preparations were injected two times with one week interval during the antler's non-growing period, the mean level of IGF-I was found to be 2,920.7ng I mL, indicating that the IGF-I concentration increased up to 8.4-folds compared with a control. After two weeks from second shot, however, the IGF-I levels decreased to the level of the control. Similar results were also obtained with both a Sika and a Red deer during the antler's growing period. Increases in the IGF-I level of up to 5.6-folds with the Sika deer and 4.3-folds with the Red deer were found. Based on the present study, it is likely that the rBST may be used as a possible candidate for an antler's growth stimulating agent.