미만성 경화 변종 갑상선 유두암 2예

• Published in: Endocrinology and metabolism (Seoul) Vol. 23; no. 6; pp. 430 - 437
• Main Authors: 원희관, Hee Kwan Won, 이명준, Myoung Jun Lee, 박주호, Joo Ho Park, 송인걸, In Girl Song, 이고은, Go Eun Lee, 정지현, Ji Hyun Jeong, 천지영, Jee Young Cheon, 설혜정, Hae Joung Sul, 임동미, Dong Mi Lim, 박근용, Keun Young Park
• Format: Journal Article
• Language: Korean
• Published: 대한내분비학회 30.12.2008
• Subjects: diffuse sclerosing variant; papillary thyroid carcinoma; 내과학
• ISSN: 2093-596X; 2093-5978

The diffuse sclerosing variant of papillary thyroid carcinoma (DSPTC) is a rare histological subtype characterized by diffuse involvement of one or both thyroid lobes, widespread lymphatic permeation, prominent fibrosis, squamous metaplasia, abundant psammoma body and lymphatic infiltration. This subtype usually occurs in young female, and exhibits a higher frequency of cervical and distant metastasis. DSPTC clinically resembles Hashimoto`s thyroiditis, and often delays the correct diagnosis. We experienced two patients with DSPTC: the one patient presented with a neck mass lasting for a month, and in the other patient, a thyroid lesion was incidentally found during a medical examination. (J Korean Endocr Soc 23:430~437, 2008)