위험 요인이 없는 젊은 여성에서 발생한 육종양 간세포암 1예

• Published in: The Korean journal of gastroenterology Vol. 47; no. 6; pp. 458 - 462
• Main Authors: 남효성, Hyo Sung Nam, 김해경, Hae Kyung Kim, 마세웅, Sae Ung Ma, 유병현, Byung Hyun Yu, 정기명, Ki Myung Jung, 공경택, Kyung Taek Gong, 이용주, Yong Ju Lee, 박태일, Tae Il Park, 허병원, Byung Won Hu, 박신희, Shin Hee Park, 나진영, Jin Yung Na
• Format: Journal Article
• Language: Korean
• Published: 대한소화기학회 30.06.2006
• Subjects: Hepatocellular carcinoma; Immunohistochemistry; Risk factor; Sarcomatoid; 내과학
• ISSN: 1598-9992; 2233-6869

A previously healthy 22-year-old woman was admitted with a complaint of right upper quadrant abdominal pain for 2 weeks. Her past history was not remarkable. On admission, HBsAg and anti-HCV were negative and a-FP was within normal range. Abdominal sonography and CT showed a mass in Liver measuring 10×11 cm with features of central necrosis and hemorrhage. On 6th hospital day, hemoperitoneum developed suddenly. She underwent emergency Laparotomy and trisegmentectomy. Intraoperative finding revealed a hemoperitoneum with a tumor filled with liquefied necrotic tissues. Microscopically, the tumor was mostly composed of pleomorphic spindle cells with abundant anastomosing vascular channels and partly composed of tumor cells with trabecular arrangement. On immunohistochemical staining, tumor cells reacted with cytokeratin and vimentin, while CD34 and hepatocyte staining revealed negative. She died 2 months after the operation. We report a case of rapidly deteriorated primary sarcomatoid hepatocellular carcinoma in a young female without any risk factor. (Korean J Gastroenterol 2006;47:458-462)