에탐부톨에 의한 호산구증가증과 전신성 증상증후군 및 이소니아지드에 의한 자가면역간염의 동시발생

Anti-tuberculosis drugs can produce levels of hepatotoxicity ranging from mild elevation of aminotransferase to severe acute hepatitis. A few cases of drug-induced autoimmune hepatitis or the drug reaction with eosinophilia and systemic symptom (DRESS) syndrome by anti-tuberculosis medications have...

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Published inThe Korean journal of gastroenterology Vol. 67; no. 5; pp. 267 - 271
Main Authors 최준혁, Joon Hyuk Choi, 허내윤, Nae Yun Heo, 박승하, Seung Ha Park, 박찬선, Chan Sun Park, 조경민, Kyeong Min Jo, 김우경, Woo Gyeong Kim, 남경한, Kyung Han Nam
Format Journal Article
LanguageKorean
Published 대한소화기학회 31.05.2016
Subjects
Antitubercular agents
autoimmune
Drug hypersensitivity syndrome
Hepatitis
내과학
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Summary:Anti-tuberculosis drugs can produce levels of hepatotoxicity ranging from mild elevation of aminotransferase to severe acute hepatitis. A few cases of drug-induced autoimmune hepatitis or the drug reaction with eosinophilia and systemic symptom (DRESS) syndrome by anti-tuberculosis medications have been reported. However, concomitant occurrence of these two disorders has not been reported. Here, we present a case of severe acute hepatitis with DRESS syndrome and autoimmune hepatitis resulting from primary standard anti-tuberculosis drugs. Both conditions were successfully treated with a systemic steroid regimen. (Korean J Gastroenterol 2016;67:267-271)
Bibliography:Korean Society of Gastroenterology
G704-000307.2016.67.5.004
ISSN:1598-9992
2233-6869