다제내성 그람양성균 감염증

• Published in: The Korean journal of medicine Vol. 88; no. 5; pp. 487 - 501
• Main Authors: 정영희, Young Hee Jung, 김홍빈, Hong Bin Kim
• Format: Journal Article
• Language: Korean
• Published: 대한내과학회 31.05.2015
• Subjects: Methicillin-resistant Staphylococcus aureus; Penicillin-resistant Streptococcus pneumoniae; Vancomycin-resistant enterococcus; 내과학; 메티실린 내성 황색포도알균; 반코마이신 내성 장알균; 페니실린 내성 폐렴사슬알균
• ISSN: 1738-9364; 2289-0769
• DOI: 10.3904/kjm.2015.88.5.487

Antimicrobial resistance threatens the effective treatment of bacterial infections and is a serious problem worldwide. Multidrug-resistant bacteria are difficult to treat and the treatment outcome is worse than with susceptible bacteria. In Korea, the antibiotic resistance rates of the major Gram-positive bacteria methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococcus (VRE), and penicillin-resistant Streptococcus pneumoniae (PRSP) are very high. Clinicians should know the risk factors for developing multidrug-resistant bacterial infection, update the changing local epidemiology of resistant bacteria, and choose appropriate antibiotics in clinical practice. The overuse and misuse of broad spectrum antibiotics should be avoided. This review focuses on the epidemiology and risk factors of MRSA, VRE, and PRSP, the major multidrug-resistant Gram-positive bacteria. (Korean J Med 2015;88:487-501)