원발성 흉막삼출성 림프종 1예

• Published in: The Korean journal of medicine Vol. 74; no. 4; pp. 441 - 444
• Main Authors: 백관미, Kwan Mi Pack, 김상위, Sang We Kim, 이상도, Sang Do Lee, 김윤지, Yoon Ji Kim, 서철원, Cheol Won Suh, 김동관, Dong Kwan Kim, 송동은, Dong Eun Song
• Format: Journal Article
• Language: Korean
• Published: 대한내과학회 01.04.2008
• Subjects: Adenosine deaminase; Primary effusion Lymphoma; 내과학; 아데노신데아미나제; 원발성 흉막삼출성 림프종
• ISSN: 1738-9364; 2289-0769

저자 등은 ADA가 증가되어 있는 편측성 흉수를 가진 환자에서 원발성 흉막삼출성 림프종 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. A 78-year-old woman was referred to this hospital because of exertional dyspnea for 2 weeks. Although she was treated with anti-tuberculous medication under the assumption that she had tuberculous pleuritis, her dyspnea continued. Physical examination revealed diminished breath sounds over the left lung field. Chest radiography showed a large left pleural effusion. The pleural effusion revealed malignant cell-dominant exudates with a high adenosine deaminase level. Serological tests were negative for HIV. Computed tomography scan of the chest and abdomen showed pleural effusion, but no mass or pathological lymph nodes were detected. The biopsy specimen of the pleura was diagnosed as malignant B-cell lymphoma with plasmacytoid features, suggesting a possibility of primary effusion lymphoma. Polymerase chain reaction assay of tumor was positive for HHV-8 DNA. She underwent pleurodesis during Video-Assisted Thoracic Surgery, and her dyspnea subsequently improved.(Korean J Med 74:441-444, 2008)