Cyclosporine에 의한 중추신경계 독성 1례

Cyclosporine is an immunosuppressant usually used to prevent renal transplantation rejection. Nephrotoxicity and hypertension are considered as the most frequent side effects of cyclosporine treatment. The neurotoxic effects of cyclosporine such as agitation, anxiety, delirium, depression and psycho...

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Bibliographic Details
Published inJournal of the Korean Society of Pediatric Nephrology Vol. 1; no. 2; pp. 179 - 182
Main Authors 이도윤, 남궁미경, 김황민, 임백근, Lee Do-Yoon, NamGoong Mee-Kyung, Kim Hwang-Min, Lim Baek-Keun
Format Journal Article
LanguageKorean
Published 1997
Subjects
Cyclosporine side effects
Henoch-Sch\"{o}nlein$ nephritis
Central nervous system toxicity
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Summary:Cyclosporine is an immunosuppressant usually used to prevent renal transplantation rejection. Nephrotoxicity and hypertension are considered as the most frequent side effects of cyclosporine treatment. The neurotoxic effects of cyclosporine such as agitation, anxiety, delirium, depression and psychosis have recently been found. Methylprednisolone may increase as well plasma concentration of cyclosporine, which leads to side effects. Here we report a $Henoch-Sch\"{o}nlein$ nephritis patient treated with cyclosporine and methylprednisolone who has experienced psychosis including visual and auditory hallucination and convulsion.
Bibliography:KISTI1.1003/JNL.JAKO199717033647137
ISSN:1226-5292
2234-4209