Anti-hyperlipidemia and Anti-arteriosclerosis Effects of Laminaria japonica in Sprague-Dawley Rats

The anti-hyperlipidemic effects of dietary supplementation with sea tangle Laminaria japonica were investigated using an animal model in which normal rats were fed either sea tangle, sea tangle ethanol extract (EE-ST) and sea tangle extracted residue (ER-ST). Total lipid and triglyceride levels in t...

Full description

Saved in:
Bibliographic Details
Published inFisheries and aquatic sciences Vol. 14; no. 4; pp. 235 - 241
Main Authors Lee, Seung-Joo, Kim, Chong-Wook, Jang, Hyuk-Jai, Cho, Soon-Yeong, Choi, Jong-Won
Format Journal Article
LanguageKorean
Published 한국수산과학회 30.12.2011
Subjects
Antihyperlipidemia
Atheroscrelosis
Sea tangle
Atheroscrelosis
Sea tangle
Antihyperlipidemia
Online AccessGet full text

Cover

More Information
Summary:The anti-hyperlipidemic effects of dietary supplementation with sea tangle Laminaria japonica were investigated using an animal model in which normal rats were fed either sea tangle, sea tangle ethanol extract (EE-ST) and sea tangle extracted residue (ER-ST). Total lipid and triglyceride levels in the serum were significantly (P < 0.05) reduced in rats fed ER-ST at a dose of 200 mg/kg body weight when compared to hyperlipidemic control rats. Significant decreases in serum total cholesterol and low density lipoprotein-cholesterol levels also occurred in rats fed ER-ST at 200 mg/kg body weight. In addition, the atherosclerosis index and superoxide dismutase in blood lipids were significantly (P < 0.05) lowered in rats fed ER-ST at 200 mg/kg body weight as compared to control rats. In conclusion, sea tangle and ER-ST exhibited beneficial anti-hyperlipidemic and anti-arteriosclerosis effects.
Bibliography:The Korean Fisheries Society
KISTI1.1003/JNL.JAKO201108040013929
ISSN:2234-1749
2234-1757